Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin

Ovarian cancer stem cells (OCSCs) are sources of tumor chemoresistance and recurrence. A hypoxic microenvironment contributes to the chemoresistance of cancer stem cells (CSCs), but the underlying mechanism is not fully understood yet. Here, we show that increased HIF‐2α expression is associated wit...

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Detalles Bibliográficos
Autores principales: He, Miao, Wu, Huizhe, Jiang, Qian, Liu, Yinuo, Han, Li, Yan, Yuanyuan, Wei, Binbin, Liu, Fangxiao, Deng, Xiaolan, Chen, Huiying, Zhao, Lin, Wang, Min, Wu, Xin, Yao, Weifan, Zhao, Haishan, Chen, Jianjun, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360369/
https://www.ncbi.nlm.nih.gov/pubmed/30536571
http://dx.doi.org/10.1002/1878-0261.12419

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