HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells

Poly(ADP‐ribose) polymerase 1 inhibitors alone or in combination with DNA damaging agents are promising clinical drugs in the treatment of cancer. However, there is a need to understand the molecular mechanisms of resistance to PARP1 inhibitors. Expression of HMGA2 in cancer is associated with poor...

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Detalles Bibliográficos
Autores principales: Hombach‐Klonisch, Sabine, Kalantari, Forouh, Medapati, Manoj Reddy, Natarajan, Suchitra, Krishnan, Sai Nivedita, Kumar‐Kanojia, Aditya, Thanasupawat, Thatchawan, Begum, Farhana, Xu, Fred Y., Hatch, Grant M., Los, Marek, Klonisch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360374/
https://www.ncbi.nlm.nih.gov/pubmed/30289618
http://dx.doi.org/10.1002/1878-0261.12390

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