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A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases
Impaired therapeutic responses to anti-inflammatory glucocorticoids (GC) in chronic respiratory diseases are partly attributable to interleukins and transforming growth factor β1 (TGF-β1). However, previous efforts to prevent induction of GC insensitivity by targeting established canonical and non-c...
Autores principales: | Li, Meina, Keenan, Christine R., Lopez-Campos, Guillermo, Mangum, Jonathan E., Chen, Qianyu, Prodanovic, Danica, Xia, Yuxiu C., Langenbach, Shenna Y., Harris, Trudi, Hofferek, Vinzenz, Reid, Gavin E., Stewart, Alastair G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360516/ https://www.ncbi.nlm.nih.gov/pubmed/30711747 http://dx.doi.org/10.1016/j.isci.2019.01.023 |
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