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Calcium channel blockade with nimodipine reverses MRI evidence of cerebral oedema following acute hypoxia

Acute cerebral hypoxia causes rapid calcium shifts leading to neuronal damage and death. Calcium channel antagonists improve outcomes in some clinical conditions, but mechanisms remain unclear. In 18 healthy participants we: (i) quantified with multiparametric MRI the effect of hypoxia on the thalam...

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Detalles Bibliográficos
Autores principales: Rowland, Matthew J, Ezra, Martyn, Winkler, Anderson, Garry, Payashi, Lamb, Catherine, Kelly, Michael, Okell, Thomas W, Westbrook, Jon, Wise, Richard G, Douaud, Gwenaëlle, Pattinson, Kyle TS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360646/
https://www.ncbi.nlm.nih.gov/pubmed/28857714
http://dx.doi.org/10.1177/0271678X17726624