Cargando…

Transcriptomic expression profiling identifies ITGBL1, an epithelial to mesenchymal transition (EMT)-associated gene, is a promising recurrence prediction biomarker in colorectal cancer

The current histopathological risk-stratification criteria in colorectal cancer (CRC) patients following a curative surgery remain inadequate. In this study, we undertook a systematic, genomewide, biomarker discovery approach to identify and validate key EMT-associated genes that may facilitate recu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsuyama, Takatoshi, Ishikawa, Toshiaki, Takahashi, Naoki, Yamada, Yasuhide, Yasuno, Masamichi, Kawano, Tatsuyuki, Uetake, Hiroyuki, Goel, Ajay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360655/ https://www.ncbi.nlm.nih.gov/pubmed/30717807 http://dx.doi.org/10.1186/s12943-019-0945-y

Ejemplares similares

A metastasis‐associated microRNA‐based liquid biopsy signature for risk‐stratification in colorectal cancer: a multicenter cohort study
por: Matsuyama, Takatoshi, et al.
Publicado: (2022)

Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia
por: Hanaoka, Marie, et al.
Publicado: (2017)

The PVT1 lncRNA is a novel epigenetic enhancer of MYC, and a promising risk-stratification biomarker in colorectal cancer
por: Shigeyasu, Kunitoshi, et al.
Publicado: (2020)

ITGBL1 Predicts a Poor Prognosis and Correlates EMT Phenotype in Gastric Cancer
por: Li, Rongkun, et al.
Publicado: (2017)

ITGBL1 promotes EMT, invasion and migration by activating NF-κB signaling pathway in prostate cancer
por: Li, Wenze, et al.
Publicado: (2019)

Evaluation of the Role of ITGBL1 in Ovarian Cancer
por: Cortez, Alexander Jorge, et al.
Publicado: (2020)

Regulatory Mechanism of ITGBL1 in the Metastasis of Colorectal Cancer
por: Qi, Lu, et al.
Publicado: (2020)

TPX2 expression is associated with poor survival in gastric cancer
por: Tomii, Chiharu, et al.
Publicado: (2017)

High expression of EphA3 (erythropoietin-producing hepatocellular A3) in gastric cancer is associated with metastasis and poor survival
por: Nasri, Baongoc, et al.
Publicado: (2017)

A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial–mesenchymal transition
por: Wang, Zhe, et al.
Publicado: (2022)

Methylation of bone morphogenetic protein 2 is associated with poor prognosis in colorectal cancer
por: Miura, Tomiyuki, et al.
Publicado: (2020)

PHLDA1 expression in ulcerative colitis: A potential role in the management of dysplasia
por: Orita, Fukuichiro, et al.
Publicado: (2021)

The effectiveness of plasma miR-33a-5p as a predictive biomarker for the efficacy of colorectal cancer chemotherapy
por: Sasaki, Megumi, et al.
Publicado: (2021)

Epithelial–Mesenchymal Transition (EMT)
por: Manfioletti, Guidalberto, et al.
Publicado: (2023)

Serum Levels of ITGBL1 as an Early Diagnostic Biomarker for Hepatocellular Carcinoma with Hepatitis B Virus Infection
por: Ye, Fei, et al.
Publicado: (2021)

ITGBL1 promotes cell migration and invasion through stimulating the TGF‐β signalling pathway in hepatocellular carcinoma
por: Huang, Wei, et al.
Publicado: (2020)

ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
por: Cheli, Yann, et al.
Publicado: (2021)

Epithelial–Mesenchymal Transition (EMT) 2021
por: Manfioletti, Guidalberto, et al.
Publicado: (2022)

Correction to: ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
por: Cheli, Yann, et al.
Publicado: (2021)

ITGBL1 transcriptionally inhibited by JDP2 promotes the development of pancreatic cancer through the TGF-beta/Smad pathway
por: Du, Tiancong, et al.
Publicado: (2022)

mFOLFOX6 plus bevacizumab to treat liver-only metastases of colorectal cancer that are unsuitable for upfront resection (TRICC0808): a multicenter phase II trial comprising the final analysis for survival
por: Yasuno, Masamichi, et al.
Publicado: (2019)

The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines
por: Kimura-Tsuchiya, Reiko, et al.
Publicado: (2014)

Characterization of gene expression profiles in HBV-related liver fibrosis patients and identification of ITGBL1 as a key regulator of fibrogenesis
por: Wang, Mingjie, et al.
Publicado: (2017)

miR-655 Is an EMT-Suppressive MicroRNA Targeting ZEB1 and TGFBR2
por: Harazono, Yosuke, et al.
Publicado: (2013)

Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
por: Ji, Qing, et al.
Publicado: (2020)

Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge
por: Jang, Dong Gil, et al.
Publicado: (2022)

Role of Metabolic Reprogramming in Epithelial–Mesenchymal Transition (EMT)
por: Kang, Hyunkoo, et al.
Publicado: (2019)

The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case
por: Cebrià-Costa, Joan Pau, et al.
Publicado: (2014)

Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance
por: Ashrafizadeh, Milad, et al.
Publicado: (2020)

Involvement of Epithelial-Mesenchymal Transition (EMT) in Autoimmune Diseases
por: Sarrand, Julie, et al.
Publicado: (2023)

Epithelial-Mesenchymal Transition (EMT): The Type-2 EMT in Wound Healing, Tissue Regeneration and Organ Fibrosis
por: Marconi, Guya D., et al.
Publicado: (2021)

Heterogeneity and plasticity of epithelial–mesenchymal transition (EMT) in cancer metastasis: Focusing on partial EMT and regulatory mechanisms
por: Li, Dandan, et al.
Publicado: (2023)

Annexin A1 Expression Is Associated with Epithelial–Mesenchymal Transition (EMT), Cell Proliferation, Prognosis, and Drug Response in Pancreatic Cancer
por: Oshi, Masanori, et al.
Publicado: (2021)

Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases
por: Zvaifler, Nathan J
Publicado: (2006)

Epithelial mesenchymal transition (EMT) in prostate growth and tumor progression
por: Grant, Campbell M., et al.
Publicado: (2013)

Epithelial mesenchymal transition (EMT) in small airways of COPD patients
por: Sohal, Sukhwinder Singh, et al.
Publicado: (2013)

dbEMT: an epithelial-mesenchymal transition associated gene resource
por: Zhao, Min, et al.
Publicado: (2015)

Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis
por: Usman, Saima, et al.
Publicado: (2021)

Quantifying the Epithelial-to-Mesenchymal Transition (EMT) from Bench to Bedside
por: Brown, Meredith S., et al.
Publicado: (2022)

MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma
por: Setlai, Botle Precious, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_boqr4nno886n3i7q5cs788i0vq