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Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells
BACKGROUND: Differentiation of induced pluripotent stem cells (iPSCs) toward hematopoietic progenitor cells (HPCs) raises high hopes for disease modeling, drug screening, and cellular therapy. Various differentiation protocols have been established to generate iPSC-derived HPCs (iHPCs) that resemble...
Autores principales: | Cypris, Olivia, Frobel, Joana, Rai, Shivam, Franzen, Julia, Sontag, Stephanie, Goetzke, Roman, Szymanski de Toledo, Marcelo A., Zenke, Martin, Wagner, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360658/ https://www.ncbi.nlm.nih.gov/pubmed/30717806 http://dx.doi.org/10.1186/s13148-019-0617-1 |
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