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Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

BACKGROUND: Differentiation of induced pluripotent stem cells (iPSCs) toward hematopoietic progenitor cells (HPCs) raises high hopes for disease modeling, drug screening, and cellular therapy. Various differentiation protocols have been established to generate iPSC-derived HPCs (iHPCs) that resemble...

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Detalles Bibliográficos
Autores principales: Cypris, Olivia, Frobel, Joana, Rai, Shivam, Franzen, Julia, Sontag, Stephanie, Goetzke, Roman, Szymanski de Toledo, Marcelo A., Zenke, Martin, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360658/
https://www.ncbi.nlm.nih.gov/pubmed/30717806
http://dx.doi.org/10.1186/s13148-019-0617-1

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