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TNF-α enhances Th9 cell differentiation and antitumor immunity via TNFR2-dependent pathways

Tumor specific Th9 cells are potential effector cells for adoptive therapy of human cancers. TNF family members OX40L, TL1A and GITRL have been shown to promote the induction of Th9 cells and antitumor immunity. However, the role of TNF-α, the prototype of the TNF superfamily cytokines, in Th9 cell...

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Detalles Bibliográficos
Autores principales:	Jiang, Yuxue, Chen, Jintong, Bi, Enguang, Zhao, Yinghua, Qin, Tianxue, Wang, Yiming, Wang, Alison, Gao, Sujun, Yi, Qing, Wang, Siqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360681/ https://www.ncbi.nlm.nih.gov/pubmed/30717817 http://dx.doi.org/10.1186/s40425-018-0494-8

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