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Modulating CRISPR gene drive activity through nucleocytoplasmic localization of Cas9 in S. cerevisiae
BACKGROUND: The bacterial CRISPR/Cas genome editing system has provided a major breakthrough in molecular biology. One use of this technology is within a nuclease-based gene drive. This type of system can install a genetic element within a population at unnatural rates. Combatting of vector-borne di...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360766/ https://www.ncbi.nlm.nih.gov/pubmed/30766726 http://dx.doi.org/10.1186/s40694-019-0065-x |