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Identification of regulatory elements from nascent transcription using dREG

Our genomes encode a wealth of transcription initiation regions (TIRs) that can be identified by their distinctive patterns of actively elongating RNA polymerase. We previously introduced dREG to identify TIRs using PRO-seq data. Here, we introduce an efficient new implementation of dREG that uses P...

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Detalles Bibliográficos
Autores principales: Wang, Zhong, Chu, Tinyi, Choate, Lauren A., Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360809/
https://www.ncbi.nlm.nih.gov/pubmed/30573452
http://dx.doi.org/10.1101/gr.238279.118