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Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs

The sequence domains underlying long noncoding RNA (lncRNA) activities, including their characteristic nuclear enrichment, remain largely unknown. It has been proposed that these domains can originate from neofunctionalized fragments of transposable elements (TEs), otherwise known as RIDLs (repeat i...

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Detalles Bibliográficos
Autores principales: Carlevaro-Fita, Joana, Polidori, Taisia, Das, Monalisa, Navarro, Carmen, Zoller, Tatjana I., Johnson, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360812/
https://www.ncbi.nlm.nih.gov/pubmed/30587508
http://dx.doi.org/10.1101/gr.229922.117