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Guide Positioning Sequencing identifies aberrant DNA methylation patterns that alter cell identity and tumor-immune surveillance networks

Aberrant DNA methylation is a distinguishing feature of cancer. Yet, how methylation affects immune surveillance and tumor metastasis remains ambiguous. We introduce a novel method, Guide Positioning Sequencing (GPS), for precisely detecting whole-genome DNA methylation with cytosine coverage as hig...

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Detalles Bibliográficos
Autores principales:	Li, Jin, Li, Yan, Li, Wei, Luo, Huaibing, Xi, Yanping, Dong, Shihua, Gao, Ming, Xu, Peng, Zhang, Baolong, Liang, Ying, Zou, Qingping, Hu, Xin, Peng, Lina, Zou, Dan, Wang, Ting, Yang, Hongbo, Jiang, Cizhong, Peng, Shaoliang, Wu, Feizhen, Yu, Wenqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360814/ https://www.ncbi.nlm.nih.gov/pubmed/30670627 http://dx.doi.org/10.1101/gr.240606.118

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