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Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson’s disease brains with Lewy body pathology
LRRK2, the gene encoding the multidomain kinase Leucine-Rich Repeat Kinase 2 (LRRK2), has been linked to familial and sporadic forms of Parkinson’s disease (PD), as well as cancer, leprosy and Crohn’s disease, establishing it as a target for discovery therapeutics. LRRK2 has been associated with a r...
Autores principales: | Mamais, Adamantios, Manzoni, Claudia, Nazish, Iqra, Arber, Charles, Sonustun, Berkiye, Wray, Selina, Warner, Thomas T., Cookson, Mark R., Lewis, Patrick A., Bandopadhyay, Rina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361106/ https://www.ncbi.nlm.nih.gov/pubmed/30055128 http://dx.doi.org/10.1016/j.brainres.2018.07.023 |
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