A neurodevelopmental TUBB2B β-tubulin mutation impairs Bim1 (yeast EB1)-dependent spindle positioning

Malformations of the human cerebral cortex can be caused by mutations in tubulins that associate to compose microtubules. Cerebral cortical folding relies on neuronal migration and on progenitor proliferation partly dictated by microtubule-dependent mitotic spindle positioning. A single amino acid c...

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Detalles Bibliográficos
Autores principales: Denarier, Eric, Brousse, Carine, Sissoko, Abdoulaye, Andrieux, Annie, Boscheron, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361202/
https://www.ncbi.nlm.nih.gov/pubmed/30674462
http://dx.doi.org/10.1242/bio.038620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361202/
https://www.ncbi.nlm.nih.gov/pubmed/30674462
http://dx.doi.org/10.1242/bio.038620

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