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Hypoxia evokes increased PDI and PDIA6 expression in the infarcted myocardium of ex-germ-free and conventionally raised mice

The prototypic protein disulfide isomerase (PDI), encoded by the P4HB gene, has been described as a survival factor in ischemic cardiomyopathy. However, the role of protein disulfide isomerase associated 6 (PDIA6) under hypoxic conditions in the myocardium remains enigmatic, and it is unknown whethe...

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Detalles Bibliográficos
Autores principales: Kiouptsi, Klytaimnistra, Finger, Stefanie, Garlapati, Venkata S., Knorr, Maike, Brandt, Moritz, Walter, Ulrich, Wenzel, Philip, Reinhardt, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361221/
https://www.ncbi.nlm.nih.gov/pubmed/30498015
http://dx.doi.org/10.1242/bio.038851