The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate

Antiretroviral therapy (ART) suppresses HIV replication, but does not cure the infection because replication-competent virus persists within latently infected CD4+ T cells throughout years of therapy. These reservoirs contain integrated HIV-1 genomes and can resupply active virus. Thus, the developm...

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Detalles Bibliográficos
Autores principales: Bobardt, Michael, Kuo, Joseph, Chatterji, Udayan, Chanda, Sumit, Little, Susan J., Wiedemann, Norbert, Vuagniaux, Gregoire, Gallay, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361451/
https://www.ncbi.nlm.nih.gov/pubmed/30716099
http://dx.doi.org/10.1371/journal.pone.0211746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361451/
https://www.ncbi.nlm.nih.gov/pubmed/30716099
http://dx.doi.org/10.1371/journal.pone.0211746

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