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Structured Crowding and Its Effects on Enzyme Catalysis

Macromolecular crowding decreases the diffusion rate, shifts the equilibrium of protein–protein and protein–substrate interactions, and changes protein conformational dynamics. Collectively, these effects contribute to enzyme catalysis. Here we describe how crowding may bias the conformational chang...

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Detalles Bibliográficos
Autores principales:	Ma, Buyong, Nussinov, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361544/ https://www.ncbi.nlm.nih.gov/pubmed/23571857 http://dx.doi.org/10.1007/128_2012_316

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