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NOTCH1 pathway activating mutations and clonal evolution in pediatric T‐cell acute lymphoblastic leukemia

Molecular mechanisms involved in the relapse of T‐cell acute lymphoblastic leukemia (T‐ALL) are not fully understood, although activating NOTCH1 signaling due to NOTCH1/FBXW7 alterations is a major oncogenic driver. To unravel the relevance of NOTCH1/FBXW7 mutations associated with relapse, we perfo...

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Detalles Bibliográficos
Autores principales:	Kimura, Shunsuke, Seki, Masafumi, Yoshida, Kenichi, Shiraishi, Yuichi, Akiyama, Masaharu, Koh, Katsuyoshi, Imamura, Toshihiko, Manabe, Atsushi, Hayashi, Yasuhide, Kobayashi, Masao, Oka, Akira, Miyano, Satoru, Ogawa, Seishi, Takita, Junko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361559/ https://www.ncbi.nlm.nih.gov/pubmed/30387229 http://dx.doi.org/10.1111/cas.13859

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