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Flexible nitrogen utilisation by the metabolic generalist pathogen Mycobacterium tuberculosis

Bacterial metabolism is fundamental to survival and pathogenesis. We explore how Mycobacterium tuberculosis utilises amino acids as nitrogen sources, using a combination of bacterial physiology and stable isotope tracing coupled to mass spectrometry metabolomics methods. Our results define core prop...

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Detalles Bibliográficos
Autores principales: Agapova, Aleksandra, Serafini, Agnese, Petridis, Michael, Hunt, Debbie M, Garza-Garcia, Acely, Sohaskey, Charles D, de Carvalho, Luiz Pedro Sório
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361586/
https://www.ncbi.nlm.nih.gov/pubmed/30702426
http://dx.doi.org/10.7554/eLife.41129