Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition

The zinc finger CCCTC-binding protein (CTCF) carries out many functions in the cell. Although previous studies sought to explain CTCF multivalency based on sequence composition of binding sites, few examined how CTCF post-translational modification (PTM) could contribute to function. Here, we perfor...

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Detalles Bibliográficos
Autores principales: Del Rosario, Brian C, Kriz, Andrea J, Del Rosario, Amanda M, Anselmo, Anthony, Fry, Christopher J, White, Forest M, Sadreyev, Ruslan I, Lee, Jeannie T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361588/
https://www.ncbi.nlm.nih.gov/pubmed/30676316
http://dx.doi.org/10.7554/eLife.42341

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