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Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus)
Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361648/ https://www.ncbi.nlm.nih.gov/pubmed/30429427 http://dx.doi.org/10.1292/jvms.18-0297 |
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author | AHMAD, Ali Anwar WAHAB, Norsham Abd YEO, Clara Wenjing OH, Serena Jocelyn Wai Yin CHEN, Hui Cheng |
author_facet | AHMAD, Ali Anwar WAHAB, Norsham Abd YEO, Clara Wenjing OH, Serena Jocelyn Wai Yin CHEN, Hui Cheng |
author_sort | AHMAD, Ali Anwar |
collection | PubMed |
description | Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination. |
format | Online Article Text |
id | pubmed-6361648 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Veterinary Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-63616482019-02-08 Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) AHMAD, Ali Anwar WAHAB, Norsham Abd YEO, Clara Wenjing OH, Serena Jocelyn Wai Yin CHEN, Hui Cheng J Vet Med Sci Wildlife Science Forty rescued common palm civets were anesthetized. Twenty animals received intramuscular injections of alfaxalone 5 mg/kg and medetomidine 0.05 mg/kg (A-M group), whereas twenty animals received 5 mg/kg of tiletamine and zolazepam (T-Z group). The A-M group was reversed with atipamazole 0.25 mg/kg. There were no significant differences in the time from anesthetic injection to induction and intubation between the A-M and T-Z groups. The time from the injection of reversal in the A-M group and the time from cessation of isoflurane in the T-Z group to extubation, first response to recovery and ambulation were longer (P<0.05) in the T-Z group. The T-Z group recorded lower (P<0.05) rectal temperatures compared to the A-M group. This study showed that both drug combinations can be used effectively for the immobilization of civets. The A-M combination provided better anesthetic depth, but with higher incidence of bradycardia and hypoxemia. The recovery time was reduced significantly as atipamezole was used as a reversal agent in the A-M combination. The Japanese Society of Veterinary Science 2018-11-15 2019-01 /pmc/articles/PMC6361648/ /pubmed/30429427 http://dx.doi.org/10.1292/jvms.18-0297 Text en ©2019 The Japanese Society of Veterinary Science This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Wildlife Science AHMAD, Ali Anwar WAHAB, Norsham Abd YEO, Clara Wenjing OH, Serena Jocelyn Wai Yin CHEN, Hui Cheng Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title_full | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title_fullStr | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title_full_unstemmed | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title_short | Comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (Paradoxurus musangus) |
title_sort | comparison of alfaxalone-medetomidine and tiletamine-zolazepam in rescued common palm civets (paradoxurus musangus) |
topic | Wildlife Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361648/ https://www.ncbi.nlm.nih.gov/pubmed/30429427 http://dx.doi.org/10.1292/jvms.18-0297 |
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