Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

This study assessed the influence of the composition of drug-free SNEDDS co-dosed with aqueous suspensions of carvedilol (CAR), cinnarizine (CIN) or R3040 on drug solubilization in a two-compartment in vitro lipolysis model. Correlation of drug logP or solubility in SNEDDS with drug solubilization d...

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Detalles Bibliográficos
Autores principales: Siqueira Jørgensen, ScheylaDaniela, Rades, Thomas, Mu, Huiling, Graeser, Kirsten, Müllertz, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361727/
https://www.ncbi.nlm.nih.gov/pubmed/30766791
http://dx.doi.org/10.1016/j.apsb.2018.07.004

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