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Construction of a Quantitative Structure Activity Relationship (QSAR) Model to Predict the Absorption of Cephalosporins in Zebrafish for Toxicity Study

Cephalosporins are beta-lactam antibiotics that are widely used in China. Five generations of cephalosporins have been introduced in clinical practice to date; moreover, some new candidates are also undergoing clinical evaluations. To improve the success rates of new drug development, we need to hav...

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Detalles Bibliográficos
Autores principales:	Liu, Ying, Zhang, Xia, Zhang, Jingpu, Hu, Changqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361752/ https://www.ncbi.nlm.nih.gov/pubmed/30761002 http://dx.doi.org/10.3389/fphar.2019.00031

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