Characterisation of a functional rat hepatocyte spheroid model

Many in vitro liver cell models, such as 2D systems, that are used to assess the hepatotoxic potential of xenobiotics suffer major limitations arising from a lack of preservation of physiological phenotype and metabolic competence. To circumvent some of these limitations there has been increased foc...

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Detalles Bibliográficos
Autores principales: Kyffin, Jonathan A., Sharma, Parveen, Leedale, Joseph, Colley, Helen E., Murdoch, Craig, Harding, Amy L., Mistry, Pratibha, Webb, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361770/
https://www.ncbi.nlm.nih.gov/pubmed/30578835
http://dx.doi.org/10.1016/j.tiv.2018.12.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361770/
https://www.ncbi.nlm.nih.gov/pubmed/30578835
http://dx.doi.org/10.1016/j.tiv.2018.12.014

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