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The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope

During meiotic prophase I, telomeres attach to and move on the nuclear envelope (NE), regulating chromosome movement to promote homologous pairing. Meiosis-specific proteins TERB1, TERB2 and MAJIN play a key role in this process. Here, we report the crystal structures of human TERB1-TERB2 and TERB2-...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Chen, Yanyan, Chen, Juan, Wang, Lijun, Nie, Leitong, Long, Juanjuan, Chang, Haishuang, Wu, Jian, Huang, Chenhui, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361898/
https://www.ncbi.nlm.nih.gov/pubmed/30718482
http://dx.doi.org/10.1038/s41467-019-08437-1