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High doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells

Stress-induced premature senescence program is known to be activated in cells by various genotoxic stressors, and oxidative stress is considered to be the main of those. To this end, many studies discover antioxidants as protective anti-aging agents. In the current study, we examined the effects of...

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Detalles Bibliográficos
Autores principales: Kornienko, Ju. S., Smirnova, I. S., Pugovkina, N. A., Ivanova, Ju. S., Shilina, M. A., Grinchuk, T. M., Shatrova, A. N., Aksenov, N. D., Zenin, V. V., Nikolsky, N. N., Lyublinskaya, O. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361906/
https://www.ncbi.nlm.nih.gov/pubmed/30718685
http://dx.doi.org/10.1038/s41598-018-37972-y