A chemical approach for global protein knockdown from mice to non-human primates

Although conventional genetic modification approaches for protein knockdown work very successfully due to the increasing use of CRISPR/Cas9, effective techniques for achieving protein depletion in adult animals, especially in large animals such as non-human primates, are lacking. Here, we report a c...

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Detalles Bibliográficos
Autores principales: Sun, Xiuyun, Wang, Jun, Yao, Xia, Zheng, Wen, Mao, Yang, Lan, Tianlong, Wang, Liguo, Sun, Yonghui, Zhang, Xinyi, Zhao, Qiuye, Zhao, Jianguo, Xiao, Rui-Ping, Zhang, Xiuqin, Ji, Guangju, Rao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361926/
https://www.ncbi.nlm.nih.gov/pubmed/30729032
http://dx.doi.org/10.1038/s41421-018-0079-1

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