Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium

The importance of neutrophils in the pathogenesis of autoimmune rheumatic diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), is increasingly recognised. Generation of reactive oxygen species (ROS) and release of neutrophil extracellular traps (NETs) by activated neut...

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Detalles Bibliográficos
Autores principales: Khawaja, Akif A., Pericleous, Charis, Ripoll, Vera M., Porter, Joanna C., Giles, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361939/
https://www.ncbi.nlm.nih.gov/pubmed/30718722
http://dx.doi.org/10.1038/s41598-018-37852-5

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