Cargando…
Regional protein expression in human Alzheimer’s brain correlates with disease severity
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that currently affects 36 million people worldwide with no effective treatment available. Development of AD follows a distinctive pattern in the brain and is poorly modelled in animals. Therefore, it is vital to widen the spatial s...
Autores principales: | Xu, Jingshu, Patassini, Stefano, Rustogi, Nitin, Riba-Garcia, Isabel, Hale, Benjamin D., Phillips, Alexander M, Waldvogel, Henry, Haines, Robert, Bradbury, Phil, Stevens, Adam, Faull, Richard L. M., Dowsey, Andrew W., Cooper, Garth J. S., Unwin, Richard D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361956/ https://www.ncbi.nlm.nih.gov/pubmed/30729181 http://dx.doi.org/10.1038/s42003-018-0254-9 |
Ejemplares similares
-
Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
por: Xu, Jingshu, et al.
Publicado: (2016) -
Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease
por: Patassini, Stefano, et al.
Publicado: (2019) -
Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia
por: Scholefield, Melissa, et al.
Publicado: (2021) -
Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer’s Disease Consistent With Cerebral Pantothenate Deficiency
por: Sang, Crystal, et al.
Publicado: (2022) -
Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson’s Disease Dementia
por: Scholefield, Melissa, et al.
Publicado: (2021)