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Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease
In early Alzheimer’s disease (AD) spatial navigation is impaired; however, the precise cause of this impairment is unclear. Recent evidence suggests that getting lost is one of the first impairments to emerge in AD. It is possible that getting lost represents a failure to use distal cues to get orie...
Autores principales: | Stimmell, Alina C., Baglietto-Vargas, David, Moseley, Shawn C., Lapointe, Valérie, Thompson, Lauren M., LaFerla, Frank M., McNaughton, Bruce L., Wilber, Aaron A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361963/ https://www.ncbi.nlm.nih.gov/pubmed/30718609 http://dx.doi.org/10.1038/s41598-018-37151-z |
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