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A transcription factor PU.1 is critical for Ccl22 gene expression in dendritic cells and macrophages

The chemokine CCL22 is predominantly produced by dendritic cells (DCs) and macrophages. CCL22 acts on CCR4-expressing cells including Th2 and Treg. Although a correlation between the CCL22-CCR4 axis and allergic diseases has been established, the mechanism of monocyte lineage-specific Ccl22 gene exp...

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Detalles Bibliográficos
Autores principales: Yashiro, Takuya, Nakano, Shiori, Nomura, Kurumi, Uchida, Yuna, Kasakura, Kazumi, Nishiyama, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361964/
https://www.ncbi.nlm.nih.gov/pubmed/30718772
http://dx.doi.org/10.1038/s41598-018-37894-9