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Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation
Translation is a highly regulated process that is perturbed in human cancers, often through activation of the PI3K/mTOR pathway which impacts directly on the ribosome recruitment phase of translation initiation. While significant research has focused on “drugging” components of the PI3K/mTOR network...
Autores principales: | Itoua Maïga, Rayelle, Cencic, Regina, Chu, Jennifer, Waller, Daniel D., Brown, Lauren E., Devine, William G., Zhang, Wenhan, Sebag, Michael, Porco Jr., John A., Pelletier, Jerry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361980/ https://www.ncbi.nlm.nih.gov/pubmed/30718665 http://dx.doi.org/10.1038/s41598-018-37666-5 |
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