Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology

The blood-brain barrier (BBB) has a major role in maintaining brain homeostasis through the specialized function of brain endothelial cells (BECs). Inflammation of the BECs and loss of their neuroprotective properties is associated with several neurological disorders, including the chronic neuro-inf...

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Detalles Bibliográficos
Autores principales: Derada Troletti, Claudio, Fontijn, Ruud D., Gowing, Elizabeth, Charabati, Marc, van Het Hof, Bert, Didouh, Imad, van der Pol, Susanne M. A., Geerts, Dirk, Prat, Alexandre, van Horssen, Jack, Kooij, Gijs, de Vries, Helga E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361981/
https://www.ncbi.nlm.nih.gov/pubmed/30718504
http://dx.doi.org/10.1038/s41419-018-1294-2

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