Single-molecule sequencing detection of N6-methyladenine in microbial reference materials

The DNA base modification N6-methyladenine (m(6)A) is involved in many pathways related to the survival of bacteria and their interactions with hosts. Nanopore sequencing offers a new, portable method to detect base modifications. Here, we show that a neural network can improve m(6)A detection at tr...

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Detalles Bibliográficos
Autores principales: McIntyre, Alexa B. R., Alexander, Noah, Grigorev, Kirill, Bezdan, Daniela, Sichtig, Heike, Chiu, Charles Y., Mason, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362088/
https://www.ncbi.nlm.nih.gov/pubmed/30718479
http://dx.doi.org/10.1038/s41467-019-08289-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362088/
https://www.ncbi.nlm.nih.gov/pubmed/30718479
http://dx.doi.org/10.1038/s41467-019-08289-9

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