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Single-molecule sequencing detection of N6-methyladenine in microbial reference materials
The DNA base modification N6-methyladenine (m(6)A) is involved in many pathways related to the survival of bacteria and their interactions with hosts. Nanopore sequencing offers a new, portable method to detect base modifications. Here, we show that a neural network can improve m(6)A detection at tr...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362088/ https://www.ncbi.nlm.nih.gov/pubmed/30718479 http://dx.doi.org/10.1038/s41467-019-08289-9 |