Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer

Regulatory T cells (Tregs) represent an important contributor to cancer immune escape, but the molecular mechanism responsible for Treg expansion in tumors is heterogeneous and unclear. Here, we investigated the role of S1P1, a receptor of the bioactive lipid sphingosine 1-phosphate (S1P), in regula...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yi-Na, Zhang, Han, Zhang, Lin, Cai, Ting-Ting, Huang, Dai-Jia, He, Jia, Ni, Huan-He, Zhou, Fang-Jian, Zhang, Xiao-Shi, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362099/
https://www.ncbi.nlm.nih.gov/pubmed/30718502
http://dx.doi.org/10.1038/s41419-018-1298-y

Ejemplares similares

Ejemplares similares