Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control

Ribosome-associated quality control (RQC) pathways monitor and respond to ribosome stalling. Using in vivo UV-crosslinking and mass spectrometry, we identified a C-terminal region in Hel2/Rqt1 as an RNA binding domain. Complementary crosslinking and sequencing data for Hel2 revealed binding to 18S r...

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Detalles Bibliográficos
Autores principales: Winz, Marie-Luise, Peil, Lauri, Turowski, Tomasz W., Rappsilber, Juri, Tollervey, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362110/
https://www.ncbi.nlm.nih.gov/pubmed/30718516
http://dx.doi.org/10.1038/s41467-019-08382-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362110/
https://www.ncbi.nlm.nih.gov/pubmed/30718516
http://dx.doi.org/10.1038/s41467-019-08382-z

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