Cargando…

The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region

The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD could be driven by other layers of genomic information independent from sequence...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandez-Jimenez, Nora, Garcia-Etxebarria, Koldo, Plaza-Izurieta, Leticia, Romero-Garmendia, Irati, Jauregi-Miguel, Amaia, Legarda, Maria, Ecsedi, Szilvia, Castellanos-Rubio, Ainara, Cahais, Vincent, Cuenin, Cyrille, Degli Esposti, Davide, Irastorza, Iñaki, Hernandez-Vargas, Hector, Herceg, Zdenko, Bilbao, Jose Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362130/ https://www.ncbi.nlm.nih.gov/pubmed/30718669 http://dx.doi.org/10.1038/s41598-018-37746-6

Ejemplares similares

Transcription Factor Binding Site Enrichment Analysis in Co-Expression Modules in Celiac Disease
por: Romero-Garmendia, Irati, et al.
Publicado: (2018)

MAGI2 Gene Region and Celiac Disease
por: Jauregi-Miguel, Amaia, et al.
Publicado: (2019)

Expression analysis in intestinal mucosa reveals complex relations among genes under the association peaks in celiac disease
por: Plaza-Izurieta, Leticia, et al.
Publicado: (2015)

A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
por: Castellanos-Rubio, Ainara, et al.
Publicado: (2019)

Human mitochondrial DNA is extensively methylated in a non-CpG context
por: Patil, Vibha, et al.
Publicado: (2019)

DNA Methylome Changes of Muscle- and Neuronal-Related Processes Precede Bladder Cancer Invasiveness
por: Bošković, Maria, et al.
Publicado: (2022)

Host Genetics and Microbiota Interactions in Colorectal Cancer: Shared or Independent Risk?
por: Romero-Garmendia, Irati, et al.
Publicado: (2022)

From Omic Layers to Personalized Medicine in Colorectal Cancer: The Road Ahead
por: Romero-Garmendia, Irati, et al.
Publicado: (2023)

Coregulation and modulation of NFκB-related genes in celiac disease: uncovered aspects of gut mucosal inflammation
por: Fernandez-Jimenez, Nora, et al.
Publicado: (2014)

DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer
por: Awada, Z., et al.
Publicado: (2019)

Unique DNA methylation signature in HPV-positive head and neck squamous cell carcinomas
por: Degli Esposti, Davide, et al.
Publicado: (2017)

Cubic regression-based degree of correction predicts the performance of whole bisulfitome amplified DNA methylation analysis
por: Fernandez-Jimenez, Nora, et al.
Publicado: (2012)

Accuracy in Copy Number Calling by qPCR and PRT: A Matter of DNA
por: Fernandez-Jimenez, Nora, et al.
Publicado: (2011)

Environmentally sensitive hotspots in the methylome of the early human embryo
por: Silver, Matt J, et al.
Publicado: (2022)

Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms
por: Shahbazi, Roghayeh, et al.
Publicado: (2023)

Novel Probiotic Bacterium Rouxiella badensis subsp. acadiensis (Canan SV-53) Modulates Gut Immunity through Epigenetic Mechanisms
por: Shahbazi, Roghayeh, et al.
Publicado: (2023)

Implication of m6A mRNA Methylation in Susceptibility to Inflammatory Bowel Disease
por: Sebastian-delaCruz, Maialen, et al.
Publicado: (2020)

Performance of the Use of Genetic Information to Assess the Risk of Colorectal Cancer in the Basque Population
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2022)

Correction: Integrative Genomics Identifies Gene Signature Associated with Melanoma Ulceration
por: Rakosy, Zsuzsa, et al.
Publicado: (2013)

Integrative Genomics Identifies Gene Signature Associated with Melanoma Ulceration
por: Rakosy, Zsuzsa, et al.
Publicado: (2013)

Genetic Variants as Predictors of the Success of Colorectal Cancer Treatments
por: Garcia-Etxebarria, Koldo, et al.
Publicado: (2023)

HPV Infection Leaves a DNA Methylation Signature in Oropharyngeal Cancer Affecting Both Coding Genes and Transposable Elements
por: Camuzi, Diego, et al.
Publicado: (2021)

Optimized DNA extraction from neonatal dried blood spots: application in methylome profiling
por: Ghantous, Akram, et al.
Publicado: (2014)

miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival
por: Degli Esposti, Davide, et al.
Publicado: (2017)

MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes
por: Ardin, Maude, et al.
Publicado: (2016)

DNA Methylation Characteristics of Primary Melanomas with Distinct Biological Behaviour
por: Ecsedi, Szilvia, et al.
Publicado: (2014)

Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation
por: Sklias, Athena, et al.
Publicado: (2021)

Pan-cancer multi-omics analysis and orthogonal experimental assessment of epigenetic driver genes
por: Halaburkova, Andrea, et al.
Publicado: (2020)

TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors
por: Ancey, Pierre-Benoit, et al.
Publicado: (2017)

The Cord Blood Insulin and Mitochondrial DNA Content Related Methylome
por: Reimann, Brigitte, et al.
Publicado: (2019)

Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure
por: Vicente, Anna Luiza Silva Almeida, et al.
Publicado: (2022)

Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age
por: Demetriou, Christiana A., et al.
Publicado: (2013)

Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch
por: Martin, Marion, et al.
Publicado: (2014)

Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles
por: Castellanos-Rubio, Idoia, et al.
Publicado: (2020)

Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors
por: Lambert, Marie-Pierre, et al.
Publicado: (2015)

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
por: Esposti, Davide Degli, et al.
Publicado: (2016)

Linking Cognitive Measures of Response Inhibition and Reward Sensitivity to Trait Impulsivity
por: Jauregi, Ainara, et al.
Publicado: (2018)

Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression
por: Siouda, Maha, et al.
Publicado: (2014)

A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease
por: Sebastian-delaCruz, M., et al.
Publicado: (2021)

Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption
por: Soares-Lima, Sheila Coelho, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_edc1r31452t3be5thh46raqi83