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Generation and characterization of novel anti-DR4 and anti-DR5 antibodies developed by genetic immunization

Development of therapeutic antibodies in oncology has attracted much interest in the past decades. More than 30 of them have been approved and are being used to treat patients suffering from cancer. Despite encouraging results, and albeit most clinical trials aiming at evaluating monoclonal antibodi...

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Detalles Bibliográficos
Autores principales: Dubuisson, Agathe, Favreau, Cécile, Fourmaux, Eric, Lareure, Sabrina, Rodrigues-Saraiva, Rafael, Pellat-Deceunynck, Catherine, El Alaoui, Said, Micheau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362131/
https://www.ncbi.nlm.nih.gov/pubmed/30718507
http://dx.doi.org/10.1038/s41419-019-1343-5