Stress-induced precocious aging in PD-patient iPSC-derived NSCs may underlie the pathophysiology of Parkinson’s disease

Parkinson’s disease (PD) is an aging-related degenerative disorder arisen from the loss of dopaminergic neurons in substantia nigra. Although many genetic mutations have been implicated to be genetically linked to PD, the low incidence of familial PD carried with mutations suggests that there must b...

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Detalles Bibliográficos
Autores principales: Zhu, Liang, Sun, Chenxi, Ren, Jie, Wang, Guangming, Ma, Rongjie, Sun, Lixin, Yang, Danjing, Gao, Shane, Ning, Ke, Wang, Zhigang, Chen, Xu, Chen, Shengdi, Zhu, Hongwen, Gao, Zhengliang, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362163/
https://www.ncbi.nlm.nih.gov/pubmed/30718471
http://dx.doi.org/10.1038/s41419-019-1313-y

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