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The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study

Few studies have focused on frailty as a predictor of mortality and readmission among inpatients in the acute care setting, especially over long follow-up periods. We conducted this study to determine the impact of the frailty on subsequent mortality and readmission in this setting. This study was a...

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Autores principales: Hao, Qiukui, Zhou, Lixing, Dong, Biao, Yang, Ming, Dong, Birong, Weil, Yuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362215/
https://www.ncbi.nlm.nih.gov/pubmed/30718784
http://dx.doi.org/10.1038/s41598-018-38072-7
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author Hao, Qiukui
Zhou, Lixing
Dong, Biao
Yang, Ming
Dong, Birong
Weil, Yuquan
author_facet Hao, Qiukui
Zhou, Lixing
Dong, Biao
Yang, Ming
Dong, Birong
Weil, Yuquan
author_sort Hao, Qiukui
collection PubMed
description Few studies have focused on frailty as a predictor of mortality and readmission among inpatients in the acute care setting, especially over long follow-up periods. We conducted this study to determine the impact of the frailty on subsequent mortality and readmission in this setting. This study was a prospective observational study conducted in the acute geriatric wards, with a three-year follow-up duration. We assessed frailty via the 36-item Frailty Index (FI), and a cut-off value of 0.25 was used to identify the presence or absence of frailty. We collected survival and readmission information through telephone interviews at 12, 24, and 36 months. We used the Cox regression model to examine the association between frailty and outcomes interested (death and readmission). The present study included 271 patients (mean age: 81.1 years old; 20.3% females), of whom 21.4% died during the 3-year follow-up period. One hundred and thirty-three patients (49.1%) were identified as being frail. The prevalence of frailty was similar in men and women (46.8% vs.58.2%, P = 0.130). Compared with non-frail patients, death and hospital readmission rates of frail patients were increased. Frailty was an independent predictor of 3-year death (adjusted hazard ratio (HR): 2.09; 95% confidence interval (CI): 1.20 to 3.63) and readmission (adjusted HR: 1.40; 95% CI: 1.04 to 1.88) after adjusting for several potential confounders. Frailty is prevalent among older inpatients and is a valuable predictor of 3-year mortality and hospital readmission in an acute care setting.
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spelling pubmed-63622152019-02-06 The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study Hao, Qiukui Zhou, Lixing Dong, Biao Yang, Ming Dong, Birong Weil, Yuquan Sci Rep Article Few studies have focused on frailty as a predictor of mortality and readmission among inpatients in the acute care setting, especially over long follow-up periods. We conducted this study to determine the impact of the frailty on subsequent mortality and readmission in this setting. This study was a prospective observational study conducted in the acute geriatric wards, with a three-year follow-up duration. We assessed frailty via the 36-item Frailty Index (FI), and a cut-off value of 0.25 was used to identify the presence or absence of frailty. We collected survival and readmission information through telephone interviews at 12, 24, and 36 months. We used the Cox regression model to examine the association between frailty and outcomes interested (death and readmission). The present study included 271 patients (mean age: 81.1 years old; 20.3% females), of whom 21.4% died during the 3-year follow-up period. One hundred and thirty-three patients (49.1%) were identified as being frail. The prevalence of frailty was similar in men and women (46.8% vs.58.2%, P = 0.130). Compared with non-frail patients, death and hospital readmission rates of frail patients were increased. Frailty was an independent predictor of 3-year death (adjusted hazard ratio (HR): 2.09; 95% confidence interval (CI): 1.20 to 3.63) and readmission (adjusted HR: 1.40; 95% CI: 1.04 to 1.88) after adjusting for several potential confounders. Frailty is prevalent among older inpatients and is a valuable predictor of 3-year mortality and hospital readmission in an acute care setting. Nature Publishing Group UK 2019-02-04 /pmc/articles/PMC6362215/ /pubmed/30718784 http://dx.doi.org/10.1038/s41598-018-38072-7 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hao, Qiukui
Zhou, Lixing
Dong, Biao
Yang, Ming
Dong, Birong
Weil, Yuquan
The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title_full The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title_fullStr The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title_full_unstemmed The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title_short The role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
title_sort role of frailty in predicting mortality and readmission in older adults in acute care wards: a prospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362215/
https://www.ncbi.nlm.nih.gov/pubmed/30718784
http://dx.doi.org/10.1038/s41598-018-38072-7
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