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Family functioning, trauma exposure and PTSD: A cross sectional study

OBJECTIVE: Only a minority of trauma-exposed individuals go on to develop post traumatic stress disorder (PTSD). Previous studies in high income countries suggest that maladaptive family functioning adversities (MFFA) in childhood may partially explain individual variation in vulnerability to PTSD f...

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Autores principales: Dorrington, Sarah, Zavos, Helena, Ball, Harriet, McGuffin, Peter, Sumathipala, Athula, Siribaddana, Sisira, Rijsdijk, Fruhling, Hatch, Stephani L., Hotopf, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362264/
https://www.ncbi.nlm.nih.gov/pubmed/30445390
http://dx.doi.org/10.1016/j.jad.2018.11.056
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author Dorrington, Sarah
Zavos, Helena
Ball, Harriet
McGuffin, Peter
Sumathipala, Athula
Siribaddana, Sisira
Rijsdijk, Fruhling
Hatch, Stephani L.
Hotopf, Matthew
author_facet Dorrington, Sarah
Zavos, Helena
Ball, Harriet
McGuffin, Peter
Sumathipala, Athula
Siribaddana, Sisira
Rijsdijk, Fruhling
Hatch, Stephani L.
Hotopf, Matthew
author_sort Dorrington, Sarah
collection PubMed
description OBJECTIVE: Only a minority of trauma-exposed individuals go on to develop post traumatic stress disorder (PTSD). Previous studies in high income countries suggest that maladaptive family functioning adversities (MFFA) in childhood may partially explain individual variation in vulnerability to PTSD following trauma. We test in a lower middle-income setting (Sri Lanka) whether: (1) MFFA is associated with trauma exposure; (2) MFFA moderates the association between exposure to trauma and later (a) PTSD (b) other psychiatric diagnoses; and (3) any association between MFFA and PTSD is explained by experiences of interpersonal violence, cumulative trauma exposure or comorbid psychopathology. METHODS: We conducted a population study of 3995 twins and 2019 singletons residing in Colombo, Sri Lanka. Participants completed the Composite International Diagnostic Interview, including nine traumatic exposures and a questionnaire on MFFA. RESULTS: 23.4% of participants reported exposure to MFFA. We found that (1) MFFA was strongly associated with trauma exposure (2) MFFA moderates the association between trauma exposure and both (a) PTSD and (b) other DSM psychiatric diagnosis. (3) This was not explained by interpersonal violence, cumulative trauma exposure or other psychopathology. CONCLUSIONS: MFFA moderates the association between trauma and PTSD, and the association between trauma and non-PTSD psychopathology.
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spelling pubmed-63622642019-02-15 Family functioning, trauma exposure and PTSD: A cross sectional study Dorrington, Sarah Zavos, Helena Ball, Harriet McGuffin, Peter Sumathipala, Athula Siribaddana, Sisira Rijsdijk, Fruhling Hatch, Stephani L. Hotopf, Matthew J Affect Disord Article OBJECTIVE: Only a minority of trauma-exposed individuals go on to develop post traumatic stress disorder (PTSD). Previous studies in high income countries suggest that maladaptive family functioning adversities (MFFA) in childhood may partially explain individual variation in vulnerability to PTSD following trauma. We test in a lower middle-income setting (Sri Lanka) whether: (1) MFFA is associated with trauma exposure; (2) MFFA moderates the association between exposure to trauma and later (a) PTSD (b) other psychiatric diagnoses; and (3) any association between MFFA and PTSD is explained by experiences of interpersonal violence, cumulative trauma exposure or comorbid psychopathology. METHODS: We conducted a population study of 3995 twins and 2019 singletons residing in Colombo, Sri Lanka. Participants completed the Composite International Diagnostic Interview, including nine traumatic exposures and a questionnaire on MFFA. RESULTS: 23.4% of participants reported exposure to MFFA. We found that (1) MFFA was strongly associated with trauma exposure (2) MFFA moderates the association between trauma exposure and both (a) PTSD and (b) other DSM psychiatric diagnosis. (3) This was not explained by interpersonal violence, cumulative trauma exposure or other psychopathology. CONCLUSIONS: MFFA moderates the association between trauma and PTSD, and the association between trauma and non-PTSD psychopathology. Elsevier/North-Holland Biomedical Press 2019-02-15 /pmc/articles/PMC6362264/ /pubmed/30445390 http://dx.doi.org/10.1016/j.jad.2018.11.056 Text en © The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dorrington, Sarah
Zavos, Helena
Ball, Harriet
McGuffin, Peter
Sumathipala, Athula
Siribaddana, Sisira
Rijsdijk, Fruhling
Hatch, Stephani L.
Hotopf, Matthew
Family functioning, trauma exposure and PTSD: A cross sectional study
title Family functioning, trauma exposure and PTSD: A cross sectional study
title_full Family functioning, trauma exposure and PTSD: A cross sectional study
title_fullStr Family functioning, trauma exposure and PTSD: A cross sectional study
title_full_unstemmed Family functioning, trauma exposure and PTSD: A cross sectional study
title_short Family functioning, trauma exposure and PTSD: A cross sectional study
title_sort family functioning, trauma exposure and ptsd: a cross sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362264/
https://www.ncbi.nlm.nih.gov/pubmed/30445390
http://dx.doi.org/10.1016/j.jad.2018.11.056
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