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Proposed mechanism for the length dependence of the force developed in maximally activated muscles
The molecular bases of the Frank-Starling law of the heart and of its cellular counterpart, the length dependent activation (LDA), are largely unknown. However, the recent discovery of the thick filament activation, a second pathway beside the well-known calcium mediated thin filament activation, is...
Autores principales: | Marcucci, Lorenzo, Washio, Takumi, Yanagida, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362285/ https://www.ncbi.nlm.nih.gov/pubmed/30718530 http://dx.doi.org/10.1038/s41598-018-36706-4 |
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