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PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL
OBJECTIVE: To examine the profile and appropriate use of antibiotics among hospitalized children. METHODS: A cross-sectional study was conducted with children who had taken antibiotics during hospitalization in a private philanthropic hospital in Southern Brazil, from January to December 2015. The d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade de Pediatria de São Paulo
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362370/ https://www.ncbi.nlm.nih.gov/pubmed/30066820 http://dx.doi.org/10.1590/1984-0462/;2019;37;1;00011 |
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author | EmyInumaru, Fernanda Silva, André Souza e Soares, Alessandra de Sá Schuelter-Trevisol, Fabiana |
author_facet | EmyInumaru, Fernanda Silva, André Souza e Soares, Alessandra de Sá Schuelter-Trevisol, Fabiana |
author_sort | EmyInumaru, Fernanda |
collection | PubMed |
description | OBJECTIVE: To examine the profile and appropriate use of antibiotics among hospitalized children. METHODS: A cross-sectional study was conducted with children who had taken antibiotics during hospitalization in a private philanthropic hospital in Southern Brazil, from January to December 2015. The data were obtained by reviewing medical records, encompassing demographic data (age, gender, ethnicity, and body weight) and clinical data (causes of hospitalization, use of antibiotics, and clinical outcome). Descriptive statistics was used to present the data. RESULTS: Of the 318 participants included in the study, 61.3% were male patients. The age range varied between 2 and 11 years, with mean age of 5.8±2.9 years. The prevalence of antibiotics was 24.4% out of the 1,346 hospitalized children. Median hospital stay was four days. The main cause of hospitalization was clinical instability, and the most commonly prescribed antibiotics was Cefazolin, mostly administered intravenously. Regarding the administration of antibiotics, 62.2% were adequately prescribed, even though underdose was 11.7%, and overdose was 14.6% in the studied patients. Antibiotic administration intervals were characterized as long in 8% of cases, and short in 3.5% of cases. CONCLUSIONS: Although the prevalence of antibiotics among hospitalized children was not that high, a considerable part of the sample presented inadequacy regarding the dosage and range of use. These data raise concerns about bacterial resistance and adverse reactions. |
format | Online Article Text |
id | pubmed-6362370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Sociedade de Pediatria de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-63623702019-02-11 PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL EmyInumaru, Fernanda Silva, André Souza e Soares, Alessandra de Sá Schuelter-Trevisol, Fabiana Rev Paul Pediatr Artigo Original OBJECTIVE: To examine the profile and appropriate use of antibiotics among hospitalized children. METHODS: A cross-sectional study was conducted with children who had taken antibiotics during hospitalization in a private philanthropic hospital in Southern Brazil, from January to December 2015. The data were obtained by reviewing medical records, encompassing demographic data (age, gender, ethnicity, and body weight) and clinical data (causes of hospitalization, use of antibiotics, and clinical outcome). Descriptive statistics was used to present the data. RESULTS: Of the 318 participants included in the study, 61.3% were male patients. The age range varied between 2 and 11 years, with mean age of 5.8±2.9 years. The prevalence of antibiotics was 24.4% out of the 1,346 hospitalized children. Median hospital stay was four days. The main cause of hospitalization was clinical instability, and the most commonly prescribed antibiotics was Cefazolin, mostly administered intravenously. Regarding the administration of antibiotics, 62.2% were adequately prescribed, even though underdose was 11.7%, and overdose was 14.6% in the studied patients. Antibiotic administration intervals were characterized as long in 8% of cases, and short in 3.5% of cases. CONCLUSIONS: Although the prevalence of antibiotics among hospitalized children was not that high, a considerable part of the sample presented inadequacy regarding the dosage and range of use. These data raise concerns about bacterial resistance and adverse reactions. Sociedade de Pediatria de São Paulo 2018-07-26 2019 /pmc/articles/PMC6362370/ /pubmed/30066820 http://dx.doi.org/10.1590/1984-0462/;2019;37;1;00011 Text en https://creativecommons.org/licenses/by/4.0/ Este é um artigo publicado em acesso aberto sob uma licença Creative Commons |
spellingShingle | Artigo Original EmyInumaru, Fernanda Silva, André Souza e Soares, Alessandra de Sá Schuelter-Trevisol, Fabiana PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title | PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title_full | PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title_fullStr | PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title_full_unstemmed | PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title_short | PROFILE AND APPROPRIATE USE OF ANTIBIOTICS AMONG CHILDREN IN A GENERAL HOSPITAL IN SOUTHERN BRAZIL |
title_sort | profile and appropriate use of antibiotics among children in a general hospital in southern brazil |
topic | Artigo Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362370/ https://www.ncbi.nlm.nih.gov/pubmed/30066820 http://dx.doi.org/10.1590/1984-0462/;2019;37;1;00011 |
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