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Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect

PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this...

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Autores principales: Miao, Zequn, Li, Luojia, Meng, Xiaoli, Guo, Lili, Cao, Di, Jia, Yanlei, He, Dongmei, Huang, Lvzhen, Wang, Lejin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362476/
https://www.ncbi.nlm.nih.gov/pubmed/30805365
http://dx.doi.org/10.1155/2019/5185780
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author Miao, Zequn
Li, Luojia
Meng, Xiaoli
Guo, Lili
Cao, Di
Jia, Yanlei
He, Dongmei
Huang, Lvzhen
Wang, Lejin
author_facet Miao, Zequn
Li, Luojia
Meng, Xiaoli
Guo, Lili
Cao, Di
Jia, Yanlei
He, Dongmei
Huang, Lvzhen
Wang, Lejin
author_sort Miao, Zequn
collection PubMed
description PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this study. Axial length, refractive error, best-corrected visual acuity (BCVA), macular scans, and adverse events were recorded before the operation (as a baseline) and in postoperative reviews taken yearly for 5 years. RESULTS: This was a 5-year research: 50% of the children (20 children, 40 eyes) participated in the 6-month review, 41% of the children (17 children, 33 eyes) participated in the 1-year review, 26% of the children (11 children, 21 eyes) participated in the 2-year review, 16% of the children (7 children, 13 eyes) participated in the 3-year review, 13% of the children (5.3 children, 11 eyes) participated in the 4-year review, and 8% of the children (3.3 children, 7 eyes) participated in the 5-year review. Compared with the baseline, axial elongation was significantly changed (P<0.05) over the 5-year period in all of the children: 6-month (P=0.003), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). The axial length was extended. No significant difference was found in refractive error between measurements taken at baseline and at the 5-year postoperative visit in all of the children: 6-month (P=0.51), 1-year (P=0.50), 2-year (P=0.46), 3-year (P=0.56), 4-year (P=0.30), and 5-year (P=0.16). There were significant differences in BCVA between measurements taken at baseline and at the postoperative 5-year visit in all the children: 6-month (P=0), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). BCVA improved in 71 eyes (83.52%), remained stable in 14 eyes (16.47%), and declined in none of the children. No serious adverse events occurred before the operation and during the 5-year follow-up period. CONCLUSION: This modified PSR could be a therapeutic treatment for high myopia.
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spelling pubmed-63624762019-02-25 Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect Miao, Zequn Li, Luojia Meng, Xiaoli Guo, Lili Cao, Di Jia, Yanlei He, Dongmei Huang, Lvzhen Wang, Lejin Biomed Res Int Research Article PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this study. Axial length, refractive error, best-corrected visual acuity (BCVA), macular scans, and adverse events were recorded before the operation (as a baseline) and in postoperative reviews taken yearly for 5 years. RESULTS: This was a 5-year research: 50% of the children (20 children, 40 eyes) participated in the 6-month review, 41% of the children (17 children, 33 eyes) participated in the 1-year review, 26% of the children (11 children, 21 eyes) participated in the 2-year review, 16% of the children (7 children, 13 eyes) participated in the 3-year review, 13% of the children (5.3 children, 11 eyes) participated in the 4-year review, and 8% of the children (3.3 children, 7 eyes) participated in the 5-year review. Compared with the baseline, axial elongation was significantly changed (P<0.05) over the 5-year period in all of the children: 6-month (P=0.003), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). The axial length was extended. No significant difference was found in refractive error between measurements taken at baseline and at the 5-year postoperative visit in all of the children: 6-month (P=0.51), 1-year (P=0.50), 2-year (P=0.46), 3-year (P=0.56), 4-year (P=0.30), and 5-year (P=0.16). There were significant differences in BCVA between measurements taken at baseline and at the postoperative 5-year visit in all the children: 6-month (P=0), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). BCVA improved in 71 eyes (83.52%), remained stable in 14 eyes (16.47%), and declined in none of the children. No serious adverse events occurred before the operation and during the 5-year follow-up period. CONCLUSION: This modified PSR could be a therapeutic treatment for high myopia. Hindawi 2019-01-22 /pmc/articles/PMC6362476/ /pubmed/30805365 http://dx.doi.org/10.1155/2019/5185780 Text en Copyright © 2019 Zequn Miao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Miao, Zequn
Li, Luojia
Meng, Xiaoli
Guo, Lili
Cao, Di
Jia, Yanlei
He, Dongmei
Huang, Lvzhen
Wang, Lejin
Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title_full Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title_fullStr Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title_full_unstemmed Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title_short Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
title_sort modified posterior scleral reinforcement as a treatment for high myopia in children and its therapeutic effect
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362476/
https://www.ncbi.nlm.nih.gov/pubmed/30805365
http://dx.doi.org/10.1155/2019/5185780
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