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Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect
PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362476/ https://www.ncbi.nlm.nih.gov/pubmed/30805365 http://dx.doi.org/10.1155/2019/5185780 |
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author | Miao, Zequn Li, Luojia Meng, Xiaoli Guo, Lili Cao, Di Jia, Yanlei He, Dongmei Huang, Lvzhen Wang, Lejin |
author_facet | Miao, Zequn Li, Luojia Meng, Xiaoli Guo, Lili Cao, Di Jia, Yanlei He, Dongmei Huang, Lvzhen Wang, Lejin |
author_sort | Miao, Zequn |
collection | PubMed |
description | PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this study. Axial length, refractive error, best-corrected visual acuity (BCVA), macular scans, and adverse events were recorded before the operation (as a baseline) and in postoperative reviews taken yearly for 5 years. RESULTS: This was a 5-year research: 50% of the children (20 children, 40 eyes) participated in the 6-month review, 41% of the children (17 children, 33 eyes) participated in the 1-year review, 26% of the children (11 children, 21 eyes) participated in the 2-year review, 16% of the children (7 children, 13 eyes) participated in the 3-year review, 13% of the children (5.3 children, 11 eyes) participated in the 4-year review, and 8% of the children (3.3 children, 7 eyes) participated in the 5-year review. Compared with the baseline, axial elongation was significantly changed (P<0.05) over the 5-year period in all of the children: 6-month (P=0.003), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). The axial length was extended. No significant difference was found in refractive error between measurements taken at baseline and at the 5-year postoperative visit in all of the children: 6-month (P=0.51), 1-year (P=0.50), 2-year (P=0.46), 3-year (P=0.56), 4-year (P=0.30), and 5-year (P=0.16). There were significant differences in BCVA between measurements taken at baseline and at the postoperative 5-year visit in all the children: 6-month (P=0), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). BCVA improved in 71 eyes (83.52%), remained stable in 14 eyes (16.47%), and declined in none of the children. No serious adverse events occurred before the operation and during the 5-year follow-up period. CONCLUSION: This modified PSR could be a therapeutic treatment for high myopia. |
format | Online Article Text |
id | pubmed-6362476 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-63624762019-02-25 Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect Miao, Zequn Li, Luojia Meng, Xiaoli Guo, Lili Cao, Di Jia, Yanlei He, Dongmei Huang, Lvzhen Wang, Lejin Biomed Res Int Research Article PURPOSE: To investigate the safety and therapeutic effect of a modified posterior scleral reinforcement (PSR) in treating high myopia. METHODS: A total of 85 highly myopic eyes in 47 children (6.3±3.6 years of age, range from 3 years to 15 years) who underwent this modified PSR were included in this study. Axial length, refractive error, best-corrected visual acuity (BCVA), macular scans, and adverse events were recorded before the operation (as a baseline) and in postoperative reviews taken yearly for 5 years. RESULTS: This was a 5-year research: 50% of the children (20 children, 40 eyes) participated in the 6-month review, 41% of the children (17 children, 33 eyes) participated in the 1-year review, 26% of the children (11 children, 21 eyes) participated in the 2-year review, 16% of the children (7 children, 13 eyes) participated in the 3-year review, 13% of the children (5.3 children, 11 eyes) participated in the 4-year review, and 8% of the children (3.3 children, 7 eyes) participated in the 5-year review. Compared with the baseline, axial elongation was significantly changed (P<0.05) over the 5-year period in all of the children: 6-month (P=0.003), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). The axial length was extended. No significant difference was found in refractive error between measurements taken at baseline and at the 5-year postoperative visit in all of the children: 6-month (P=0.51), 1-year (P=0.50), 2-year (P=0.46), 3-year (P=0.56), 4-year (P=0.30), and 5-year (P=0.16). There were significant differences in BCVA between measurements taken at baseline and at the postoperative 5-year visit in all the children: 6-month (P=0), 1-year (P=0), 2-year (P=0), 3-year (P=0), 4-year (P=0), and 5-year (P=0). BCVA improved in 71 eyes (83.52%), remained stable in 14 eyes (16.47%), and declined in none of the children. No serious adverse events occurred before the operation and during the 5-year follow-up period. CONCLUSION: This modified PSR could be a therapeutic treatment for high myopia. Hindawi 2019-01-22 /pmc/articles/PMC6362476/ /pubmed/30805365 http://dx.doi.org/10.1155/2019/5185780 Text en Copyright © 2019 Zequn Miao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Miao, Zequn Li, Luojia Meng, Xiaoli Guo, Lili Cao, Di Jia, Yanlei He, Dongmei Huang, Lvzhen Wang, Lejin Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title | Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title_full | Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title_fullStr | Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title_full_unstemmed | Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title_short | Modified Posterior Scleral Reinforcement as a Treatment for High Myopia in Children and Its Therapeutic Effect |
title_sort | modified posterior scleral reinforcement as a treatment for high myopia in children and its therapeutic effect |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362476/ https://www.ncbi.nlm.nih.gov/pubmed/30805365 http://dx.doi.org/10.1155/2019/5185780 |
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