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Laminin as a Potent Substrate for Large-Scale Expansion of Human Induced Pluripotent Stem Cells in a Closed Cell Expansion System

The number of high-quality cells required for engineering an adult human-sized bioartificial organ is greater than one billion. Until the emergence of induced pluripotent stem cells (iPSCs), autologous cell sources of this magnitude and with the required complexity were not available. Growing this n...

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Detalles Bibliográficos
Autores principales: Paccola Mesquita, Fernanda C., Hochman-Mendez, Camila, Morrissey, Jacquelynn, Sampaio, Luiz C., Taylor, Doris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362483/
https://www.ncbi.nlm.nih.gov/pubmed/30805013
http://dx.doi.org/10.1155/2019/9704945