Age-Appropriateness of Porcine Models Used for Cell Transplantation

Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental p...

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Detalles Bibliográficos
Autores principales: Tohyama, Shugo, Kobayashi, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362526/
https://www.ncbi.nlm.nih.gov/pubmed/30525991
http://dx.doi.org/10.1177/0963689718817477
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author Tohyama, Shugo
Kobayashi, Eiji
author_facet Tohyama, Shugo
Kobayashi, Eiji
author_sort Tohyama, Shugo
collection PubMed
description Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs.
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spelling pubmed-63625262019-02-15 Age-Appropriateness of Porcine Models Used for Cell Transplantation Tohyama, Shugo Kobayashi, Eiji Cell Transplant Commentary Pigs have traditionally been used for preclinical experiments, and body size-matching is important for cell therapy in animal models used for preclinical trials. It has been shown that the efficacy of the transplanted cells is dependent on the response of the host heart and the age of experimental pigs. SAGE Publications 2018-12-10 2019-02 /pmc/articles/PMC6362526/ /pubmed/30525991 http://dx.doi.org/10.1177/0963689718817477 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Commentary
Tohyama, Shugo
Kobayashi, Eiji
Age-Appropriateness of Porcine Models Used for Cell Transplantation
title Age-Appropriateness of Porcine Models Used for Cell Transplantation
title_full Age-Appropriateness of Porcine Models Used for Cell Transplantation
title_fullStr Age-Appropriateness of Porcine Models Used for Cell Transplantation
title_full_unstemmed Age-Appropriateness of Porcine Models Used for Cell Transplantation
title_short Age-Appropriateness of Porcine Models Used for Cell Transplantation
title_sort age-appropriateness of porcine models used for cell transplantation
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362526/
https://www.ncbi.nlm.nih.gov/pubmed/30525991
http://dx.doi.org/10.1177/0963689718817477
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