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A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex

The multisubunit CCR4–NOT mRNA deadenylase complex plays important roles in the posttranscriptional regulation of gene expression. The NOT4 E3 ubiquitin ligase is a stable component of the CCR4–NOT complex in yeast but does not copurify with the human or Drosophila melanogaster complex. Here we show...

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Detalles Bibliográficos
Autores principales:	Keskeny, Csilla, Raisch, Tobias, Sgromo, Annamaria, Igreja, Cátia, Bhandari, Dipankar, Weichenrieder, Oliver, Izaurralde, Elisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362812/ https://www.ncbi.nlm.nih.gov/pubmed/30692204 http://dx.doi.org/10.1101/gad.320952.118

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