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TMEM16A in Cystic Fibrosis: Activating or Inhibiting?

The inflammatory airway disease cystic fibrosis (CF) is characterized by airway obstruction due to mucus hypersecretion, airway plugging, and bronchoconstriction. The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is dysfunctional in CF, leading to defects in epithelial...

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Detalles Bibliográficos
Autores principales: Kunzelmann, Karl, Ousingsawat, Jiraporn, Cabrita, Inês, Doušová, Tereza, Bähr, Andrea, Janda, Melanie, Schreiber, Rainer, Benedetto, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362895/
https://www.ncbi.nlm.nih.gov/pubmed/30761000
http://dx.doi.org/10.3389/fphar.2019.00003