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TMEM16A in Cystic Fibrosis: Activating or Inhibiting?
The inflammatory airway disease cystic fibrosis (CF) is characterized by airway obstruction due to mucus hypersecretion, airway plugging, and bronchoconstriction. The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is dysfunctional in CF, leading to defects in epithelial...
Autores principales: | Kunzelmann, Karl, Ousingsawat, Jiraporn, Cabrita, Inês, Doušová, Tereza, Bähr, Andrea, Janda, Melanie, Schreiber, Rainer, Benedetto, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362895/ https://www.ncbi.nlm.nih.gov/pubmed/30761000 http://dx.doi.org/10.3389/fphar.2019.00003 |
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