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Rhein shows potent efficacy against non-small-cell lung cancer through inhibiting the STAT3 pathway
BACKGROUND: Non-small-cell lung cancer (NSCLC) comprises about 85% of all lung cancers and is usually diagnosed at an advanced stage with poor prognosis. The IL-6/STAT3 signaling pathway plays a pivotal role in NSCLC biology. Rhein is a lipophilic anthraquinone extensively found in medicinal herbs....
Autores principales: | Yang, Lehe, Li, Jifa, Xu, Lingyuan, Lin, Shichong, Xiang, Youqun, Dai, Xuanxuan, Liang, Guang, Huang, Xiaoying, Zhu, Jiandong, Zhao, Chengguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362962/ https://www.ncbi.nlm.nih.gov/pubmed/30774444 |
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